The Museum of Natural History was established on September 30, 1976 by the University of the Philippines.

This museum consists of preserved biological and zoological specimens, wood samples; by-products of microorganism, and also thousands of living plants/trees maintained in a separate location. This museum also serves as a reference for science and a center for documentation, research, and information. It has a diverse collection of more than 200,000 preserved Philippine animals, plants, cultures of living microorganisms, and other biota that showcase the country’s rich biodiversity.

It houses most of the priceless collections of birds and small mammals of the late Dr. Dioscoro Rabor, and has in its hortorium a diverse collection of living plants.

A multi-colored diorama of Philippine flora and fauna and video presentations on biodiversity are special museum features. Exhibits feature, among others, the Philippine eagle, tamaraw, tarsier; snails in Mt. Makiling and Laguna de Bay; Philippine plants, forests, shells; Philippine cobras, marine turtles and mammals; and a Philippine map made of 4,012 locusts and lahar from Mt. Pinatubo.

For 40 years now, the UPLB Museum of Natural History serves as a center for research and documentation of Philippine biodiversity. Albeit meager funds, UPLB MNH continues to lead in the biodiversity research activities in the country and implementation of its mandate on preserving and promoting its valuable resources – its hundreds of thousands of holdings of precious biological specimens, preserved records of its life forms, of the Philippines’ natural heritage.

The museum is implementing under its banner programs a number of projects/studies on Philippine Cave Biodiversity and Biodiversity of Small Islands in the Philippines, with funds mostly from income generated from its visitor’s program, sale of books and cultures and services such as identification of biological specimens.

Other researches receive funding from the UPLB Basic Research Program, the National Research Council of the Philippines (NRCP), Department of Science and Technology (DOST), Commission on Higher Education (CHED), Philippine Council for Agriculture, Aquatic, Forestry and Natural Resources Research and Development (PCARRD) and other government institutions

The museum also have a number of collaborative endeavors with government and private (NGO and corporate) organizations and academic and research institutions abroad.